This hotel is located in the Old Town district of Wittenberg, next door to the Luther House. It offers free Wi-Fi, regional cuisine and a daily breakfast buffet. The modern rooms at the Best Western Stadtpalais Wittenberg include satellite TV. Some rooms have a balcony. The Best Western's Wittenberger Hof restaurant offers food from the Saxony-Anhalt region and a variety of drinks. The restaurant has a terrace and guests are also welcome to relax in the lounge with open fireplace. Spa facilities at the Best Western Stadtpalais Wittenberg include a beauty area and sauna (opens daily from 18:00). Wittenberg University and Wittenberg Train Station are a 5-minute walk away. The A9 motorway is 15 minutes away. Parking spaces and an underground garage are available.

Guests arriving by car should travel via Wallstraße to access the underground car park.